Increased incidence trend of low-grade and high-grade neuroendocrine neoplasms
| Autor: | Emanuele Leoncini, Guido Rindi, Michail K. Shafir, Stefania Boccia, Katina Aleksovska, Paolo Boffetta |
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| Přispěvatelé: | Leoncini, E. and Boffetta, P. and Shafir, M. and Aleksovska, K. and Boccia, S. and Rindi, G. |
| Jazyk: | angličtina |
| Předmět: |
Male
Pediatrics Pathology cancer incidence Endocrinology Diabetes and Metabolism data extraction low grade neuroendocrine neoplasm Pacific Islander 0302 clinical medicine Endocrinology systematic review High-grade middle aged Surveillance Epidemiology and End Results Medicine African American Cancer Aged 80 and over very elderly Adult Incidence (epidemiology) adult Incidence neuroendocrine carcinoma sensitivity analysi Annual Percent Change Neuroendocrine Tumors female Neuroendocrine priority journal 030220 oncology & carcinogenesis cancer grading factual database Original Article Neuroendocrine Tumor United State medicine.medical_specialty ethnic difference Low-grade sex difference prevalence tumor localization 030209 endocrinology & metabolism Caucasian Article 03 medical and health sciences Incidence trends geographic distribution Humans cancer registry human Aged Settore MED/08 - ANATOMIA PATOLOGICA Asian business.industry Neuroendocrine neoplasm Confidence interval United States Anatomical sites pathology Neoplasm Grading business trend study high grade neuroendocrine neoplasm SEER Program |
| Zdroj: | Endocrine |
| ISSN: | 1355-008X |
| DOI: | 10.1007/s12020-017-1273-x |
| Popis: | Purpose: The incidence of neuroendocrine neoplasms is increasing. This work aimed at: (i) establishing worldwide incidence trend of low-grade neuroendocrine neoplasms; (ii) defining the incidence and temporal trend of high-grade neuroendocrine neoplasms in USA utilizing the Surveillance Epidemiology and End Results database; (iii) comparing trends for low-grade vs. high-grade neuroendocrine neoplasms. Methods: We conducted a literature search on MEDLINE and Scopus databases and incidence trends were plotted for 1973-2012. The Surveillance Epidemiology and End Results database was used to identify incidence rates in USA for 1973-2012. Incidence rates were stratified according to histological grade, gender and ethnicity. Trends were summarized as annual percent change and corresponding 95% confidence interval. Results: 11 studies were identified involving 72,048 cases; neuroendocrine neoplasm incidence rates increased over time in all countries for all sites, except for appendix. In Surveillance Epidemiology and End Results low-grade neuroendocrine neoplasm incidence rate increased from 1.09 in 1973 to 3.51 per 100,000 in 2012. During this interval, high-grade neuroendocrine neoplasm incidence rate increased from 2.54 to 10.52 per 100,000. African Americans had the highest rates of digestive neuroendocrine neoplasms with male prevalence in high-grade. Conclusions: Our data indicate an increase in the incidence of neuroendocrine neoplasms as a worldwide phenomenon, affecting most anatomical sites and involving both low-grade and high-grade neoplasms. © 2017, The Author(s). |
| Databáze: | OpenAIRE |
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