The impact of route of anesthesia on maternal and fetal ischemia modified albumin levels at cesarean section: a prospective randomized study
| Autor: | Gamze Sinem Caglar, Selda Demirtas, Perihan Erdogdu, Aslı Yarcı Gursoy, Rabia Seker |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Cord Birth weight Serum albumin Serum Albumin Human Anesthesia General Anesthesia Spinal Young Adult Ischemia Pregnancy medicine Anesthesia Obstetrical Humans Prospective Studies Serum Albumin Oxygen saturation (medicine) Fetus biology business.industry Cesarean Section Infant Newborn Obstetrics and Gynecology medicine.disease Fetal Blood Pregnancy Complications Blood pressure Anesthesia Cord blood Pediatrics Perinatology and Child Health biology.protein Female business Biomarkers |
| Zdroj: | Journal of perinatal medicine. 41(5) |
| ISSN: | 1619-3997 |
| Popis: | Objective: Ischemia modified albumin has been shown to increase in ischemic situations, and has also been shown to increase in fetal cord blood in deliveries by cesarean section. The aim of this study is to reveal whether anesthesia has an impact on maternal and fetal cord ischemia modified albumin levels. Methods: Seventy two women with uncomplicated term pregnancies were randomized to spinal (n=37) or general anesthesia (n=35) groups. The blood pressure, oxygen saturation, and pulse rate of the patients were recorded during the procedure. Maternal blood samples of ischemia modified albumin (IMA) were taken 10 min from the start of the procedure. The fetal cord blood samples of IMA were taken immediately after birth. Results: Maternal (0.99±0.19 vs. 0.80±0.27) and fetal (1.00±0.21 vs. 0.70±0.26) IMA levels were significantly higher in the general anesthesia group. Fetal IMA levels were positively correlated with maternal gravidity (r=0.31; P=0.008), parity (r=0.25; P=0.028), and fetal birth weight (r=0.23, P=0.045). Also, as time from incision to delivery lengthens, fetal IMA levels increase (r=0.29, P=0.012). Conclusion: Fetal cord ischemia modified albumin levels were higher in the general anesthesia group, therefore, it is proposed that regional anesthesia should be the preferred route of anesthesia for an elective cesarean section, at least until the impact of high fetal cord IMA levels are manifested. |
| Databáze: | OpenAIRE |
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