Studies on the sensitivity and specificity of the Limulus amebocyte lysate test and rabbit pyrogen assays
| Autor: | Dony J, M J Devleeschouwer, M F Cornil |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Gram-positive bacteria
Limulus amebocyte lysate test Limulus test Sodium Chloride Gram-Positive Bacteria Applied Microbiology and Biotechnology Microbiology Animals Candida albicans Limulus Test Candida Bacteriological Techniques Ecology biology Pyrogens Microchemistry biology.organism_classification Yeast Limulus amebocyte lysate Bacterial endotoxin Rabbits Drug Contamination Water Microbiology Bacteria Research Article Food Science Biotechnology |
| Zdroj: | Applied and Environmental Microbiology. 50:1509-1511 |
| ISSN: | 1098-5336 0099-2240 |
| DOI: | 10.1128/aem.50.6.1509-1511.1985 |
| Popis: | The sensitivity and specificity of the Limulus amebocyte lysate test and rabbit pyrogen assay were studied by means of artificially contaminated parenterals. Various gram-negative and gram-positive bacterial strains were used as was one strain of the yeast Candida albicans. The numbers of organisms needed to elicit positive responses in distilled water and normal saline were recorded and compared. The sensitivity and specificity of the Limulus amebocyte lysate assay for the detection of bacterial endotoxin from gram-negative bacteria were demonstrated. Variable results were recorded with gram-positive bacteria and Candida albicans. |
| Databáze: | OpenAIRE |
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