Structural determination of ananatoside A: An unprecedented 15-membered macrodilactone-containing glycolipid from Pantoea ananatis
| Autor: | Eric Déziel, Serge Lavoie, Charles Gauthier, Sylvain Milot, Sarah Martinez, Marianne Piochon |
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| Rok vydání: | 2019 |
| Předmět: |
Models
Molecular 0303 health sciences Molecular Structure Pantoea 030306 microbiology Chemistry Stereochemistry Organic Chemistry Molecular Conformation General Medicine Biochemistry Gas Chromatography-Mass Spectrometry Analytical Chemistry Lactones 03 medical and health sciences Glycolipid Tandem Mass Spectrometry Pantoea ananatis Glycolipids Conformational isomerism Two-dimensional nuclear magnetic resonance spectroscopy 030304 developmental biology |
| Zdroj: | Carbohydrate Research. 471:13-18 |
| ISSN: | 0008-6215 |
| Popis: | The bacterium Pantoea ananatis was reported to produce glycolipid biosurfactants of unknown structures. Herein, we present the isolation and structural determination of ananatoside A, the main congener of a new family of 15-membered macrodilactone-containing glucolipids. The structure of ananatoside A was elucidated via chemical degradation and spectroscopic methods including 1D/2D NMR analysis, tandem MS/MS, GC-MS, HR-ESI-TOF-MS, MALDI-TOF-MS, and polarimetry. Computational methods were used to predict the most abundant conformers of ananatoside A. |
| Databáze: | OpenAIRE |
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