Spectrum of histological changes reactive to prosthetic breast implants: A clinopathological study of 84 patients
| Autor: | Peter Russell, Gary Yeoh, Elaine Jenkins |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Foreign-body giant cell Time Factors Breast Implants medicine.medical_treatment Mammary gland Prosthesis Pathology and Forensic Medicine Metaplasia medicine Humans Breast Histiocyte Aged Histocytochemistry business.industry Foreign-Body Reaction Dacron patch Anatomy Middle Aged medicine.disease medicine.anatomical_structure Female medicine.symptom business Complication Calcification |
| Zdroj: | Pathology. 28:232-235 |
| ISSN: | 0031-3025 |
| DOI: | 10.1080/00313029600169044 |
| Popis: | A wide range of host reactions can be produced in response to prosthetic breast implants. Although the spectrum of histological changes is well described in the literature, the chronology and relative occurrence of these changes are not well documented. Examination of 161 capsulectomy specimens from 84 women suggested the following chronological sequence of tissue response: fibrous scar tissue; histiocyte response; foreign body giant cell reaction to extruded or exposed material including polyurethane and Dacron patch; synovial-like metaplasia; and calcification. Fibrous scar tissue was seen in all implants. Histiocytic response was noted in 107/161 of the specimens and a foreign body giant cell reaction to polyurethane was seen only in the two Meme implants. Synovial-like metaplasia was less common than previously reported, occurring in 45/161 of specimens after a mean in situ duration of 11.7 years. This peculiar process was seen only in association with a prominent histiocytic response and was not associated with calcification. Dystrophic calcification, which has been reported as occurring rarely in implant capsules, was seen in 15/161 of our specimens after a mean in situ duration of 17.7 years. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect