Effect of pulmonary hypertension on outcome of pulmonary tuberculosis
| Autor: | Neda Behzadnia, Mohammad Reza Masjedi, Mohammadreza Masjedi, Majid Marjani, Davood Mansouri, Parvaneh Baghaei shiva, Majid Malekmohammad, Babak Sharif-kashani, Ali Akbar Velayati, Payam Tabarsi |
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| Rok vydání: | 2013 |
| Předmět: |
Microbiology (medical)
Male medicine.medical_specialty Tuberculosis Survival Substance-Related Disorders Hypertension Pulmonary lcsh:QR1-502 Pulmonary arterial pressure Doppler echocardiography Iran Logistic regression lcsh:Microbiology lcsh:Infectious and parasitic diseases Pulmonary hypertension Pulmonary tuberculosis Internal medicine Medicine Humans lcsh:RC109-216 Tuberculosis Pulmonary Retrospective Studies Medicine(all) medicine.diagnostic_test business.industry Middle Aged medicine.disease Prognosis Echocardiography Doppler Infectious Diseases Early Diagnosis Lung disease Echocardiography Concomitant Cardiology Female business |
| Zdroj: | Brazilian Journal of Infectious Diseases, Volume: 18, Issue: 5, Pages: 487-490, Published: SEP 2014 Brazilian Journal of Infectious Diseases, Vol 18, Iss 5, Pp 487-490 (2014) Brazilian Journal of Infectious Diseases v.18 n.5 2014 Brazilian Journal of Infectious Diseases Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
| ISSN: | 1678-4391 |
| Popis: | Background: This study performed at the National Research Institute of Tuberculosis and Lung Disease, Tehran, Iran, aimed to evaluate the effect of concomitant pulmonary hypertension on the outcome of pulmonary tuberculosis. Methods: New cases of pulmonary tuberculosis were recruited for the study. Pulmonary hypertension was defined as systolic pulmonary arterial pressure ≥35 mm Hg estimated by transthoracic Doppler echocardiography. We assessed the relationship between pulmonary hypertension and mortality during the six-month treatment of tuberculosis. Results: Of 777 new cases of pulmonary tuberculosis, 74 (9.5%) had systolic pulmonary arterial pressure ≥35 mm Hg. Ten of them (13.5%) died during treatment compared to 5% of cases with pulmonary arterial pressure less than 35 mm Hg (p = 0.007). Logistic regression analysis showed that pulmonary hypertension and drug abuse remained independently associated with mortality (OR = 3.1; 95% CI: 1.44–6.75 and OR = 4.4; 95% CI: 2.35–8.17, respectively). Conclusion: A significant association was found between mortality and presence of pulmonary hypertension and drug abuse among new cases of pulmonary tuberculosis. Keywords: Tuberculosis, Pulmonary hypertension, Echocardiography, Survival |
| Databáze: | OpenAIRE |
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