A Case of Extraskeletal Ewing's Sarcoma Arising from Duodenum

Autor:	Yeon Hee Park, Hyun Bae Son, Sung-Ho Kim, Yo Ahn Suh, Seung Sook Lee, Sang Il Kim, Kui Sung Choi, Seong Jun Choi, Baek Yeol Ryoo, Yoong Ju Kweon, Dae Han Kim
Rok vydání:	2002
Předmět:	Cancer Research Pathology medicine.medical_specialty biology CD68 business.industry CD99 Vimentin medicine.disease medicine.anatomical_structure Oncology Primitive neuroectodermal tumor Duodenum medicine biology.protein Immunohistochemistry Extraskeletal Ewing's Sarcoma Sarcoma business
Zdroj:	Cancer Research and Treatment. 34:461-465
ISSN:	2005-9256 1598-2998
Popis:	Extraskeletal Ewing's sarcomas (EES) are rare. Recently, Ewing's sarcoma of the bone, primitive neuroectodermal tumor (PNET), Askin tumor and EES have been included into the family of Ewing's tumors, due to the overlapping features relating to their clinico-pathological and cytogenetic appearance. We experienced a case of an EES arising from the duodenum in a 14-year-old girl who presented with hematemesis and epigastric discomfort. A duodenal biopsy specimen revealed the infiltration of small round cells and rich vasculatures, with immunohistochemical finding of MIC-2 (CD99) (+), vimentin (+), CD56 (NCAM) (+), LCA (-), T-cell (-), B-cell (-), CD43 (-) and CD68 (-). She was treated with several cycles of multiagent chemotherapy, and achieved an initial partial response, but rapid progression of tumor followed, so she was treated with surgical excision. This is the first case report of an EES arising from the duodenum in the literature.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a14937713c101169198a7f8f3b47b21 https://doi.org/10.4143/crt.2002.34.6.461 Zobrazit plný text záznamu