Hemodynamic Effects of Intravenous PGE1 on Patients with Arterial Occlusive Disease of the Leg
| Autor: | Ryu Nakayama, Masafumi Hirai, Michio Nanki |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors medicine.medical_treatment Occlusive disease Hemodynamics Arterial Occlusive Diseases Blood Pressure 030204 cardiovascular system & hematology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Heart Rate Internal medicine medicine Humans Popliteal Artery 030212 general & internal medicine Alprostadil Prostaglandin E1 Hemodynamic effects Aged Gangrene Leg Chemotherapy business.industry Prostaglandins E Temperature Blood flow Middle Aged medicine.disease Surgery body regions chemistry Regional Blood Flow Cardiology Female Crest Cardiology and Cardiovascular Medicine business Blood Flow Velocity |
| Zdroj: | Angiology. 36:407-413 |
| ISSN: | 1940-1574 0003-3197 |
| Popis: | In 42 patients with arterial occlusive disease of the leg, the hemodynamic effects of prostaglandin E1 (PGE1) given intravenously were studied. Blood pres sure of the leg and crest time of the pulse wave did not change significantly, while increases in blood flow at the calf and foot, amplitude of the pulse wave, velocity, and skin temperature at the foot and toes were significant. Skin tem perature of the calf dropped significantly. The increase in blood flow, velocity, and skin temperature was significantly more dominant in the distal part of the leg than that in the proximal part. In separate observation of individuals, 12 of the 66 legs with arterial occlusive disease (18%) showed a decrease in skin tem perature at the toes. The steal phenomenon was observed most frequently in limbs with rest pain, gangrene, or both. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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