Antihyperalgesia by α2-GABAA receptors occurs via a genuine spinal action and does not involve supraspinal sites

Autor: Uwe Rudolph, Jean-Marc Fritschy, Gonzalo E. Yévenes, James M. Cook, Dietmar Benke, Alessandra Di Lio, Jolly Paul, Hanns Ulrich Zeilhofer, William T. Ralvenius, Louis Scheurer, Robert Witschi
Přispěvatelé: University of Zurich, Zeilhofer, Hanns Ulrich
Rok vydání: 2013
Předmět:
Male
10050 Institute of Pharmacology and Toxicology
Pharmacology
2738 Psychiatry and Mental Health
Benzodiazepines
Mice
GABA
0302 clinical medicine
pain/analgesics
Neuropathic pain
Analgesia
Benzodiazepine
Spinal cord
Mouse model
Medicine
Neuropharmacology
Pain Measurement
0303 health sciences
GABAA receptor
Chronic pain
Imidazoles
analgesia
animal models
Psychiatry and Mental health
Nociception
medicine.anatomical_structure
3004 Pharmacology
Hyperalgesia
Female
Original Article
medicine.symptom
benzodiazepine
Agonist
medicine.drug_class
mouse model
610 Medicine & health
Mice
Transgenic
neuropharmacology
03 medical and health sciences
Animals
Humans
GABA-A Receptor Agonists
030304 developmental biology
neuropathic pain
business.industry
spinal cord
medicine.disease
Receptors
GABA-A
Mice
Inbred C57BL
HEK293 Cells
570 Life sciences
biology
business
Neuroscience
030217 neurology & neurosurgery
Zdroj: Neuropsychopharmacology
Neuropsychopharmacology, 39 (2)
ISSN: 1740-634X
0893-133X
Popis: Neuropsychopharmacology, 39 (2)
ISSN:0893-133X
ISSN:1740-634X
Databáze: OpenAIRE
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