Supplementary Materials and Methods, Supplementary Table 1, and Supplementary Figures 1 and 2 from MPT0B098, a Novel Microtubule Inhibitor That Destabilizes the Hypoxia-Inducible Factor-1α mRNA through Decreasing Nuclear–Cytoplasmic Translocation of RNA-Binding Protein HuR

Autor: Jang-Yang Chang, Joseph T. Tseng, Wen-Yu Pan, Chi-Yen Chang, Kuang-Hsing Shih, Wen-Yang Lai, Ching-Chuan Kuo, Jing-Ping Liou, Yun-Ching Cheng
Rok vydání: 2023
DOI: 10.1158/1535-7163.22500639.v1
Popis: PDF - 361KB, Supplementary Materials and Methods; Table S1: Primary Antibodies and secondary antibodies; Figure S1: Effect of MPT0B098 on the organizations of cellular microtubule network; Figure S2: Effect of MPT0B098 on HIF-regulated genes in A549 cells; Figure S3: MPT0B098 inhibits HuR translocation from the nucleus to the cytoplasm in HONE-1 and PC3 cells.
Databáze: OpenAIRE