Exosomes derived from human umbilical cord mesenchymal stem cells promote osteogenesis through the AKT signaling pathway in postmenopausal osteoporosis
| Autor: | Shi-Wei Ren, Guang-Qing Cao, Qing-Run Zhu, Min-Gang He, Fang Wu, Su-Mei Kong, Zhao-Yan Zhang, Qiang Wang, Feng Wang |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Aging. 14(24) |
| ISSN: | 1945-4589 |
| Popis: | Postmenopausal osteoporosis (PMO) is a relatively common disease characterized by low bone mass and microstructural changes of trabecular bone. The reduced bone strength is caused a variety of complications, including fragility fracture and sarcopenia. We used CCK-8 and EdU assays to evaluate cell proliferation rates. The osteogenesis effect was detected using ALP staining, alizarin red staining, and q-PCR. |
| Databáze: | OpenAIRE |
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