A prospective randomized trial of vagotomy in chronic duodenal ulceration: 4-year follow-up
| Autor: | M. Palmer, C. G. Koffman, Elder Jb, P. F. Schofield, S. M. Mantoudis, Gillespie Ie, Ganguli Pc, D. E. F. Tweedle, D. J. Hay |
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| Rok vydání: | 1983 |
| Předmět: |
Adult
Diarrhea Male medicine.medical_specialty Time Factors medicine.medical_treatment Vagotomy Gastroenterology Pyloroplasty law.invention Random Allocation Postoperative Complications Randomized controlled trial Duodenal ulceration Recurrence law Internal medicine Truncal vagotomy medicine Humans Prospective Studies Vagotomy Proximal Gastric Pylorus Clinical Trials as Topic business.industry Incidence (epidemiology) Heartburn Surgery Duodenal Ulcer Chronic Disease Vomiting Female medicine.symptom business |
| Zdroj: | British Journal of Surgery. 70:342-345 |
| ISSN: | 1365-2168 0007-1323 |
| DOI: | 10.1002/bjs.1800700611 |
| Popis: | A total of 153 patients (124 male and 29 female) with uncomplicated chronic duodenal ulceration were studied in a prospective, randomized trial of proximal gastric vagotomy (PGV) and truncal vagotomy and pyloroplasty (TVP), conducted in four Manchester hospitals. Of these, 137 patients have now been followed up for 2·5 to 5·5 (mean 4·1) yr. There have been 15 (21 per cent) recurrent ulcers following PGV compared with 5 (7·5 per cent) after TVP (P < 0·05). A satisfactory functional result was obtained in 82 per cent of patients after TVP compared with 73 per cent following PGV and there was little difference between the groups with regard to the incidence of dumping, heartburn and vomiting. There was significantly more diarrhoea following TVP (13 per cent) compared to PGV (1·4 per cent) but this represented only a minor clinical problem. |
| Databáze: | OpenAIRE |
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