The Association Between Age at Initiation of Alcohol Consumption and Type 2 Diabetes Mellitus: A Cohort Study of 0.5 Million Persons in China
| Autor: | Haoxin Li, Huajun Long, Zengzhi Zhang, Zhengming Chen, Liming Li, Yu Guo, Ling Yang, Yiping Chen, Junning Fan, Tao Huang, Huaidong Du, Canqing Yu, Zheng Bian, Jun Lv, Junshi Chen |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male China Alcohol Drinking Epidemiology alcohol consumption 030209 endocrinology & metabolism Type 2 diabetes Underage Drinking Lower risk drinking duration Cohort Studies 03 medical and health sciences 0302 clinical medicine Cognition Environmental health Medicine Humans AcademicSubjects/MED00860 030212 general & internal medicine Prospective cohort study Association (psychology) Chinese Proportional hazards model business.industry alcohol Type 2 Diabetes Mellitus Original Contribution Middle Aged medicine.disease Confidence interval Diabetes Mellitus Type 2 Female type 2 diabetes business Alcohol consumption Demography Cohort study |
| Zdroj: | American Journal of Epidemiology |
| ISSN: | 1476-6256 0002-9262 |
| Popis: | It is well known that alcohol consumption is associated with type 2 diabetes mellitus. However, the association of age at initiation of alcohol consumption and duration of alcohol drinking with type 2 diabetes mellitus among Chinese adults is not fully understood. This study was based on data from the China Kadoorie Biobank, which included 512,712 participants aged 30–79 years who were living in China in 2004–2008. A Cox proportional hazards model was used to estimate the association of AAI and drinking duration with type 2 diabetes. After adjustment for potential covariates, ages at alcohol initiation (AAIs) of 18.1–29.0 years, 29.1–39.0 years, and >39.0 years were associated with 22% (95% confidence interval (CI): 14, 30), 25% (95% CI: 17, 33), and 32% (95% CI: 24, 39) lower hazards of type 2 diabetes compared with abstaining, respectively. Drinking durations of 30.0 years were associated with 18% (95% CI: 4, 33) and 20% (95% CI: 3, 40) higher hazards of type 2 diabetes, compared with AAI 18.1–29.0 years and drinking duration |
| Databáze: | OpenAIRE |
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