Large Pleural Effusion Secondary to Primary Signet-Ring Cell Adenocarcinoma of the Lung
| Autor: | Sara Moustafa, Sarah Baroud, Halah Ibrahim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Lung signet ring cell adenocarcinoma Pulmonology business.industry Pleural effusion General Engineering histopathology (hp) left-sided pleural effusion respiratory system medicine.disease digestive system diseases Signet ring cell adenocarcinoma respiratory tract diseases medicine.anatomical_structure Oncology primary signet ring cell adenocarcinoma of the lung Medicine immunohistochemistry staining business |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Primary signet-ring cell adenocarcinomas (SRCA) that occur outside the gastrointestinal tract are rare with few cases reported in the literature. They carry a poor prognosis and can be a challenge to diagnose. In this case report, we present the case of a 69-year-old female who presented to our hospital with a large left-sided pleural effusion. The findings seen on histopathology and immunohistochemistry (IHC) staining of the pleural fluid were consistent with primary signet-ring cell adenocarcinoma of the lung, and further investigations excluded a secondary source of malignancy. To the best of our knowledge, this is the first reported case of pleural effusion without an underlying lung mass diagnosed as primary signet-ring cell adenocarcinoma of the lung. Given how rare primary signet-ring cell adenocarcinoma of the lung is, it is important for physicians to carry out a comprehensive diagnostic workup to differentiate between primary and metastatic signet-ring cell adenocarcinoma as this will determine prognosis and treatment. |
| Databáze: | OpenAIRE |
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