Long-term outcome of intractable constipation treated by sacral neuromodulation: a comparison between children and adults
| Autor: | Stephanie O. Breukink, Paul T.J. Janssen, Laurents P. S. Stassen, Marc A. Benninga, Y. M. Meyer, S.M.J. van Kuijk, Nicole D. Bouvy, Jarno Melenhorst |
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| Přispěvatelé: | MUMC+: KIO Kemta (9), Epidemiologie, RS: NUTRIM - R2 - Liver and digestive health, RS: SHE - R1 - Research (OvO), MUMC+: MA AIOS Heelkunde (9), Surgery, MUMC+: MA Heelkunde (9), RS: NUTRIM - R2 - Gut-liver homeostasis, RS: NUTRIM - R1 - Metabolic Syndrome, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, ARD - Amsterdam Reproduction and Development, Paediatric Gastroenterology |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Sacrum Constipation Adolescent DISORDERS Electric Stimulation Therapy 030230 surgery 03 medical and health sciences 0302 clinical medicine Quality of life children QUALITY-OF-LIFE FECAL INCONTINENCE ADOLESCENTS adults MANAGEMENT Medicine Fecal incontinence Humans Cleveland Clinic constipation score MODULATION Child Defecation NERVE-STIMULATION Retrospective Studies business.industry Gastroenterology Age Factors Sacral neuromodulation constipation medicine.disease IDIOPATHIC CONSTIPATION Bodily pain Treatment Outcome Sacral nerve stimulation quality of life Physical therapy SLOW-TRANSIT CONSTIPATION Functional constipation 030211 gastroenterology & hepatology Female Intractable constipation medicine.symptom business SF-36 HEALTH SURVEY |
| Zdroj: | Colorectal Disease, 20(2), 134-143. Wiley Colorectal disease, 20(2), 134-143. Wiley-Blackwell |
| ISSN: | 1462-8910 |
| Popis: | AIM Sacral neuromodulation (SNM) is a minimally invasive therapy for functional constipation (FC) and is most often used to treat adults. Recent studies suggest that SNM may also beneficial in children. However, comparative data regarding preferred age of SNM for FC are lacking. Therefore, long-term results of SNM for FC were compared between children and adults. METHOD All patients treated with SNM for FC between 2004 and 2015 were evaluated. Outcomes of children (age 10-18 years) were compared with those for adults (≥ 18 years). The primary end-point was a defaecation frequency of three or more times per week, which is consistent with the ROME-III criteria. Secondary outcomes were quality of life (QoL; SF-36) and the Cleveland Clinic Constipation Score. RESULTS One hundred and eighty patients (45 children, 135 adults) were eligible for SNM. The mean age was 15.8 (children) and 41.4 years (adults). One hundred and twenty-six patients received permanent SNM (38 children, 88 adults). Mean follow-up was 47 months in both groups. Defaecation frequency increased in both groups after SNM compared with baseline. Defaecation frequency in adults was higher than in children. The increased defaecation frequency was maintained during the entire follow-up period in both groups. QoL of children was impaired compared with the Dutch population with regard to bodily pain, general health and vitality. Adults had worse QoL with regard to physical functioning, bodily pain, general health, vitality and social functioning compared with the Dutch population. QoL of children did not differ from adults. CONCLUSION Sacral neuromodulation (SNM) should be considered in children ( |
| Databáze: | OpenAIRE |
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