Postprandial Metabolism and Vascular Function: Impact of Aging and Physical Activity Level
| Autor: | Katherine Bode, Edralin A. Lucas, Christina M. Sciarrillo, Nicholas A. Koemel, Madison Dixon, Sam R. Emerson, Nathaniel D.M. Jenkins |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Meal Nutrition and Dietetics business.industry Area under the curve Medicine (miscellaneous) General Medicine Metabolism 030204 cardiovascular system & hematology medicine.disease Physical activity level 03 medical and health sciences 0302 clinical medicine Endocrinology Postprandial medicine.anatomical_structure Internal medicine medicine Orthopedics and Sports Medicine 030212 general & internal medicine Endothelial dysfunction Vascular function business Artery |
| Zdroj: | International Journal of Sport Nutrition and Exercise Metabolism. 30:412-419 |
| ISSN: | 1543-2742 1526-484X |
| DOI: | 10.1123/ijsnem.2020-0063 |
| Popis: | The consumption of a high-fat meal can induce postprandial lipemia and endothelial dysfunction. The authors assessed the impact of age and physical activity on metabolic and vascular outcomes following meal consumption in healthy adults. The authors recruited four groups: younger active (age 22.1 ± 1.4 years; n = 9), younger inactive (age 22.6 ± 3.7 years; n = 8), older active (age 68.4 ± 7.7 years; n = 8), and older inactive (age 67.7 ± 7.2 years; n = 7). The metabolic outcomes were measured at the baseline and hourly for 6 hr post high-fat meal consumption (12 kcal/kg; 63% fat). Flow-mediated dilation was measured at the baseline, 2 hr, and 4 hr postmeal. The total area under the curve for triglycerides was significantly lower in the more active groups, but did not differ based on age (younger active = 6.5 ± 1.4 mmol/L × 6 hr, younger inactive = 11.7 ± 4.8, older active = 6.8 ± 2.7, older inactive = 12.1 ± 1.7; p = .0004). After adjusting for artery diameter, flow-mediated dilation differed between groups at the baseline (younger active = 4.8 ± 1.6%, younger inactive = 2.5 ± 0.5, older active = 3.4 ± 0.9, older inactive = 2.2 ± 0.4; p p = .04). These findings highlight the beneficial effect of regular physical activity on postprandial lipemia, independent of age. |
| Databáze: | OpenAIRE |
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