Palatal Erythema with Histological Psoriasiform Pattern: An Enigmatic Oral Finding Shared by a Range of Conditions
| Autor: | Tali Shani, Leon Gillman, Nadav Astman, Ayelet Zlotogorski Hurvitz, Yuli Goldman, Ori Platner, Ilana Kaplan, Marilena Vered, Aviv Barzilai, Gavriel Chaushu, Shoshana Reiter, Yehuda Zadik |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Adult Male Palate Hard Pathology medicine.medical_specialty Erythema Adolescent Physical examination Case Reports Hereditary mucoepithelial dysplasia Asymptomatic Pathology and Forensic Medicine 03 medical and health sciences Young Adult 0302 clinical medicine Psoriasis medicine Mucositis Humans Child Retrospective Studies medicine.diagnostic_test business.industry Middle Aged medicine.disease 030104 developmental biology medicine.anatomical_structure Oncology Otorhinolaryngology 030220 oncology & carcinogenesis Histopathology Female Hard palate medicine.symptom business Mouth Diseases |
| Zdroj: | Head Neck Pathol |
| ISSN: | 1936-0568 |
| Popis: | Long standing, asymptomatic, well-demarcated erythema of the hard palate with a histopathological psoriasiform pattern comprises a challenging diagnosis. We present a series of patients with such clinical and histological findings and discuss the possible diagnoses. We collected all patients with palatal erythematous lesions that had well-documented clinical examination. Excluded were patients with definitive diagnosis of oral infections (e.g. candidiasis), neoplastic/pre-neoplastic lesions, auto-immune diseases, reactive lesions, blood disorders and vascular malformations. Thirteen patients (six females, seven males, age range 11–56 years) were included. Histopathologically, a psoriasiform pattern was observed in all biopsied lesions. One patient was diagnosed with hereditary mucoepithelial dysplasia (HMD) and four with cutaneous psoriasis. The remaining eight patients were otherwise healthy. A combination of persistent, asymptomatic palatal erythematous lesion with psoriasis-like histopathology may represent an oral manifestation of HMD or psoriasis, concomitant to extra-oral features. In lack of any known medical background, the term "oral psoriasiform mucositis" is suggested. |
| Databáze: | OpenAIRE |
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