Body fat percentage is a better marker than body mass index for determining inflammation status in polycystic ovary syndrome
| Autor: | Nurul Ilma, R. Muharam, Amalia Shadrina, Budi Wiweko, Kanadi Sumapraja, Herbert Situmorang, Rachmat Dediat Kapnosa Hasani, Andon Hestiantoro |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
lcsh:QH471-489 procalcitonin Reproductive medicine Physiology 030209 endocrinology & metabolism lcsh:Gynecology and obstetrics Body fat percentage Procalcitonin 03 medical and health sciences 0302 clinical medicine medicine lcsh:Reproduction Congenital adrenal hyperplasia lcsh:RG1-991 Body mass index Polycystic ovary syndrome Inflammation 030219 obstetrics & reproductive medicine business.industry Hyperandrogenism Obstetrics and Gynecology medicine.disease Polycystic ovary Reproductive Medicine Body fat Etiology Original Article business |
| Zdroj: | International Journal of Reproductive Biomedicine International Journal of Reproductive BioMedicine, Vol 16, Iss 10, Pp 623-628 (2018) |
| ISSN: | 2476-3772 2476-4108 |
| DOI: | 10.29252/ijrm.16.10.623 |
| Popis: | Background Polycystic ovary syndrome (PCOS) is an endocrinopathic disorder most commonly experienced by women of reproductive age, and it is characterized by a low-grade chronic inflammatory condition. Excessive fat deposit has been long considered as an etiological factor in the pathogenesis of this inflammatory condition. Currently, body mass index (BMI) or percentage of body fat is used as a marker to assess the body fat composition of a person. Objective To determine whether BMI or body fat percentage (BFP) can be used as a better marker for measuring inflammation related to body fat accumulation in polycystic ovary syndrome patients. Materials and methods This study took place at the Center for Reproductive Medicine, Yasmin Clinic, Cipto Mangunkusumo Hospital from January to December 2015. In this cross-sectional study, 32 reproductive age women with PCOS according to the Rotterdam criteria (2003) participated. Women with hyperandrogenism caused by non-classic congenital adrenal hyperplasia, pregnant and lactating women, etc., were excluded. Some variables such as BMI, clinical hyperandrogenism sign, BFP, and inflammatory markers were assessed and statistically analyzed. Results From a total of 32 subjects of the study, BFP had a significant positive correlation with procalcitonin levels (r=0.35; p=0.048), while BMI did not (r=0.27; p=0.131). Conclusion BFP can be used as a better marker for measuring inflammation related to body fat accumulation in PCOS subjects. |
| Databáze: | OpenAIRE |
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