Risk of Local Failure in Breast Cancer Patients With Lobular Carcinoma In Situ at the Final Surgical Margins: Is Re-excision Necessary?
Autor: | Saveli Goldberg, Mina N. Shenouda, A.R. Keruakous, Andrzej Niemierko, Alphonse G. Taghian, Betro T. Sadek, Rita Abi Raad |
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Rok vydání: | 2013 |
Předmět: |
Adult
Reoperation Risk Cancer Research Surgical margin medicine.medical_specialty Neoplasm Residual medicine.medical_treatment Lobular carcinoma Breast Neoplasms Unnecessary Procedures Mastectomy Segmental Young Adult Breast cancer medicine Humans Radiology Nuclear Medicine and imaging Cumulative incidence Treatment Failure Aged Proportional Hazards Models Retrospective Studies Aged 80 and over Radiation business.industry Carcinoma in situ Hazard ratio Lumpectomy Radiotherapy Dosage Middle Aged medicine.disease Surgery Carcinoma Lobular Oncology Female Neoplasm Recurrence Local business Carcinoma in Situ Mastectomy |
Zdroj: | International Journal of Radiation Oncology*Biology*Physics. 87:726-730 |
ISSN: | 0360-3016 |
Popis: | Purpose: To compare the outcome of patients with invasive breast cancer both with and without lobular carcinoma in situ (LCIS)-positive/close surgical margins after breast-conserving treatment. Methods and Materials: We retrospectively studied 2358 patients with T1-T2 invasive breast cancer treated with lumpectomy and radiation therapy from January 1980 to December 2009. Median age was 57 years (range, 24-91 years). There were 82 patients (3.5%) with positive/close LCIS margins ( |
Databáze: | OpenAIRE |
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