An Ophthalmic Insight into Novel Coronavirus 2019 Disease: A Comprehensive Review of the Ocular Manifestations and Clinical Hazards
| Autor: | Elham A Gad, Sarah Zaher Addeen, Sara S Elsheikh, Mostafa A. Soliman, Amani E Badawi, Walid Shaban Abdella, Rami Abd-Rabu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
genetic structures Ocular Pathology Disease Review Article Cochrane Library Novel coronavirus 2019 Retina 03 medical and health sciences 0302 clinical medicine Ocular transmission Medicine business.industry Incidence (epidemiology) Retrospective cohort study Contact lens Conjunctivitis Dermatology Severe acute respiratory syndrome coronavirus-2 eye diseases Natural history Posterior segment of eyeball Ophthalmology Tear 030221 ophthalmology & optometry business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Current Ophthalmology |
| ISSN: | 2452-2325 |
| Popis: | Purpose: To discuss the ocular manifestations provoked by novel coronavirus 2019 (COVID-19) disease in humans, the natural history of the disease in the eye, and its treatment. Methods: We designed a narrative review of the ocular manifestations of COVID-19 based on the literature published till July 30, 2020. The databases were PubMed, Scopus, Cochrane Library, Google Scholar, and ScienceDirect. The inclusion criteria were (1) all types of clinical studies and (2) the topic was COVID-19 and its association to the eye regarding the current guidelines. Results: From 168 abstracts screened, 61 papers fully filled the inclusion criteria after the full-text screening. The 61 records include 13 case reports, 17 prospective (case series or cross-sectional) studies, 8 retrospective studies, 12 literature reviews (one systematic review), and 11 letters to the editor. The majority of the papers agreed that ophthalmic manifestations due to COVID-19 were few and rarely encountered. The main ocular pathology seemed to be conjunctivitis, where the viral polymerase chain reaction also happened to be most detectable. Posterior segment or neuro-ophthalmic manifestations were scarce. Viral genome detection in the eye as well as viral portal of entry to the globe is still vague. Conclusion: The exact incidence of ocular manifestations in COVID-19 disease is uncertain. Conjunctivitis is the most prevalent ocular manifestation. It is still a debate whether the eye is a portal of entry for infection. |
| Databáze: | OpenAIRE |
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