High frequency repetitive transcranial magnetic stimulation of supplementary motor cortex for obsessive compulsive disorder
| Autor: | Khurshid A. Khurshid |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Obsessive-Compulsive Disorder medicine.medical_treatment Prefrontal Cortex behavioral disciplines and activities Gyrus Cinguli 03 medical and health sciences 0302 clinical medicine mental disorders medicine Humans Deep transcranial magnetic stimulation Prefrontal cortex Anterior cingulate cortex business.industry Motor Cortex General Medicine Transcranial Magnetic Stimulation humanities Transcranial magnetic stimulation Dorsolateral prefrontal cortex 030104 developmental biology medicine.anatomical_structure nervous system Adjunctive treatment Orbitofrontal cortex business Neuroscience 030217 neurology & neurosurgery Motor cortex |
| Zdroj: | Medical hypotheses. 137 |
| ISSN: | 1532-2777 |
| Popis: | Obsessive compulsive disorder (OCD) is a common psychiatric disorder that can lead to significant dysfunction. It is treated with medications and or cognitive behavior therapy. Many patients with OCD do not respond to above mentioned conventional treatments. OCD is also a disorder with well delineated neuropathology in brain areas that form cortico-striato-thalamocortical loop. Transcranial magnetic stimulation (TMS) can not only offer a noninvasive treatment modality for many of these patients but can also specifically and beneficially affect involved neuronal areas. TMS stimulation of various brain areas including supplementary motor cortex, dorsolateral prefrontal cortex, orbitofrontal cortex and anterior cingulate cortex has been found to be beneficial in alleviating OCD symptoms in various studies. Low frequency and less often high frequency TMS of these areas has been found to be effective. High frequency deep TMS, as opposed to conventional TMS, of medial prefrontal cortex and anterior cingulate cortex was found to be effective and is approved as an adjunctive treatment option for severe OCD. There is no consensus as to the target stimulation site and optimal TMS stimulation protocol that can achieve maximum improvement in OCD symptoms. We hypothesize that high frequency r-TMS of supplementary motor cortex will alleviate OCD symptoms. |
| Databáze: | OpenAIRE |
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