Origin and Evolution of the Neo-Sex Chromosomes in Pamphagidae Grasshoppers through Chromosome Fusion and Following Heteromorphization
| Autor: | Nikolay B. Rubtsov, Ilyas Yerkinovich Jetybayev, Olesya Georgievna Buleu, Alexander G. Bugrov, Anton Bogomolov |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
neo-sex lcsh:QH426-470 Biology Article Fluorescent in situ hybridization neo-Y 03 medical and health sciences neo-X Chromosome regions Chromosome 19 evolution Genetics Pamphagidae chromosome DNA libraries grasshoppers chromosome microdissection chromosome painting Genetics (clinical) Chromosome Karyotype Chromosome 17 (human) lcsh:Genetics 030104 developmental biology Chromosome 21 Chromosome 22 |
| Zdroj: | Genes, Vol 8, Iss 11, p 323 (2017) Genes Genes; Volume 8; Issue 11; Pages: 323 |
| ISSN: | 2073-4425 |
| Popis: | In most phylogenetic lineages, the evolution of sex chromosomes is accompanied by their heteromorphization and degradation of one of them. The neo-sex chromosomes are useful model for studying early stages of these processes. Recently two lineages of the neo-sex chromosomes on different stages of heteromorphization was discovered in Pamphagidae family. The neo-sex chromosome heteromorphization was analyzed by generation of DNA probes derived from the neo-Xs and neo-Ys followed with chromosome painting in nineteen species of Pamphagidae family. The homologous regions of the neo-sex chromosomes were determined in closely related species with the painting procedure and image analysis with application of the Visualization of the Specific Signal in Silico software package. Results of these analyses and distribution of C-positive regions in the neo-sex chromosomes revealed details of the heteromorphization of the neo-sex chromosomes in species from both phylogenetic lineages of Pamphagidae grasshoppers. The hypothetical mechanism of the neo-Y degradation was suggested. It includes expansion of different repeats from the proximal neo-Y chromosome region by inversions, spreading them towards distal region. Amplification of these repeats leads to formation of C-positive regions and elimination of the C-negative regions located between them. |
| Databáze: | OpenAIRE |
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