Mycophenolate Mofetil Therapy in Refractory Inflammatory Eye Disease
| Autor: | Claudio F. Perez, Juan Verdaguer, Cristian Carpentier, Leonidas Traipe, Federica Solanes, Miguel Cuchacovich, Enzo Castiglione, Francisco A Villarroel |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Eye disease Mycophenolic acid Cohort Studies Uveitis 03 medical and health sciences 0302 clinical medicine Prednisone Internal medicine medicine Humans Pharmacology (medical) Chile Retrospective Studies Inflammation Keratitis Pharmacology business.industry Retrospective cohort study Mycophenolic Acid medicine.disease Surgery Ophthalmology Treatment Outcome 030104 developmental biology Cohort 030221 ophthalmology & optometry Female business Immunosuppressive Agents Scleritis medicine.drug Cohort study |
| Zdroj: | Journal of Ocular Pharmacology and Therapeutics. 32:55-61 |
| ISSN: | 1557-7732 1080-7683 |
| DOI: | 10.1089/jop.2015.0044 |
| Popis: | Purpose: To study the efficacy and incidence of treatment-related side effects of mycophenolate mofetil (MMF) therapy in patients with noninfectious inflammatory eye diseases. Methods: Retrospective cohort study of 27 Chilean patients treated for noninfectious inflammatory eye diseases using MMF therapy over a 10-year period. Main outcome measures were: ability to control ocular inflammation and to taper prednisone to ≤10 mg daily (treatment success); incidence of treatment-related side effects. Results: The proportion of patients with sustained control of inflammation was 81.48% at 6 months. Additionally 55.56% and 22.22% of patients succeeded in tapering their prednisone to 5–10 mg/day and |
| Databáze: | OpenAIRE |
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