Potent antagonists of vasopressin antidiuretic activity that lack the .beta.,.beta.-cyclopentamethylene-.beta.-mercaptopropionic acid substitution at position 1
| Autor: | Nelson C. F. Yim, Heidi G. Bryan, Richard Edwards, Michael L. Moore, L. B. Kinter, Dulcie B. Schmidt, F L Stassen, Hsin Lan Chang, William F. Huffman, Grace Heckman |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
chemistry.chemical_classification
Kidney Medulla Receptors Vasopressin Vasopressin medicine.medical_specialty Receptors Angiotensin Swine Vasopressins Chemistry Cell Membrane Antagonist Biological activity Peptide hormone Antidiuretic Activity Cyclic peptide Structure-Activity Relationship Endocrinology Internal medicine Drug Discovery medicine Animals Molecular Medicine Beta (finance) Mercaptopropionic acid Adenylyl Cyclases |
| Zdroj: | Journal of Medicinal Chemistry. 29:2425-2426 |
| ISSN: | 1520-4804 0022-2623 |
| DOI: | 10.1021/jm00162a001 |
| Popis: | Synthese d'acide diethyl-3,3 mercapto-3 propionique S-protege et application a la synthese d'analogues de vasopressine. Activite biologique |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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