Serum ghrelin levels in patients with Behcet’s disease
| Autor: | Haydar Uçak, Savaş Öztürk, Ilker Erden, Selma Bakar Dertlioglu, Suleyman Aydin, Demet Cicek, Betül Demir |
|---|---|
| Přispěvatelé: | Tıp Fakültesi |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
lcsh:Internal medicine Dermatology Disease Behcet's disease Gastroenterology metabolic syndrome 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Insulin resistance Behcet's Disease Internal medicine insulin resistance medicine lcsh:Dermatology Immunology and Allergy In patient lcsh:RC31-1245 Original Paper business.industry digestive oral and skin physiology lcsh:RL1-803 medicine.disease 030220 oncology & carcinogenesis ghrelin Etiology Ghrelin Metabolic syndrome business Behcet’s disease Systemic vasculitis |
| Zdroj: | Advances in Dermatology and Allergology, Vol 33, Iss 6, Pp 450-456 (2016) Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii |
| ISSN: | 2299-0046 |
| Popis: | Öztürk, Savaş (Balikesir Author) Introduction: Behcet's disease (BD) is a chronic, relapsing, systemic vasculitis of unknown etiology. Aim: To measure serum ghrelin levels in BD patients and healthy controls and to investigate its association with metabolic syndrome (MetS). Material and methods: Thirty BD patients and 30 healthy individuals were enrolled in the study. Ghrelin levels were measured in blood samples using ELISA. Results: The mean serum ghrelin level in BD patients (28.57 +/- 14.04) was significantly lower compared to healthy controls (40.72 +/- 23.21) (p = 0.01). The mean serum ghrelin level in BD patients who had MetS (24.18 +/- 12.73) was lower compared to BD patients who did not have MetS (30.77 +/- 14.45), but this difference was not significant (p > 0.05). Conclusions: Ghrelin levels were lower in BD patients compared to healthy controls. There was no association between reduced ghrelin levels and MetS; however, there was a negative correlation between ghrelin levels and disease activity. |
| Databáze: | OpenAIRE |
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