Additional file 6 of Human cortical spheroids with a high diversity of innately developing brain cell types

Autor: De Kleijn, Kim M. A., Zuure, Wieteke A., Straasheijm, Kirsten R., Martens, Marijn B., Avramut, M. Cristina, Koning, Roman I., Martens, Gerard J. M.
Rok vydání: 2023
DOI: 10.6084/m9.figshare.22617484
Popis: Additional file 6: Fig. S6. Robust presence of both neuroectoderm-derived and mesoderm-derived cell types in two independently grown day-150 (d150) human cortical spheroid (hCS) batches, with slightly different ratios in cell-type composition. (A) Log10-converted fold change (FC) of median GAPDH-normalized mRNA expression of markers for various brain cell types in batch-1 relative to batch-12 d150 hCSs. Each bar represents the median of the expression of all cell-type-specific markers for that brain cell type. (B) Log10-converted FC of median GAPDH-normalized mRNA expression of cell-type-specific markers for various brain cell types in batch-1 relative to batch-12 d150 hCSs. See Additional file 16 for markers used. SC: stem cell; NPC: neural progenitor cell; EXC: excitatory neuron; INH: inhibitory neuron; ASTR: astrocyte; OPC: oligodendrocyte precursor cell; pOL: pre-myelinating oligodendrocyte; MG: microglia; ENDO: endothelial cell.
Databáze: OpenAIRE