Comparative response of normal and cirrhotic rats to intravenously injected bacteria
| Autor: | Fritz Schweinburg, Alexander M. Rutenburg, Irving Koven, Jacob Fine, Edmund Sonnenblick |
|---|---|
| Rok vydání: | 1959 |
| Předmět: |
medicine.medical_specialty
Lung biology Bacteria Portal vein Spleen Urine biology.organism_classification Liver Cirrhosis Experimental General Biochemistry Genetics and Molecular Biology Rats Excretion Endocrinology medicine.anatomical_structure Internal medicine Immunology Injections Intravenous medicine Escherichia coli Animals Blood stream Escherichia coli Infections Clearance |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 101(2) |
| ISSN: | 0037-9727 |
| Popis: | SummaryLabelled (I131) bacteria infused into portal vein of normal rats were promptly cleared and destroyed with release of ionic I131 and its prompt excretion into the urine. In cirrhotic rats the clearance process was normal, but capacity to destroy bacteria was impaired. This resulted in persistence of ingested bacteria and of “bacteria bound” radioactivity in liver, lung, and spleen, and continued reseeding of the blood stream from such foci. |
| Databáze: | OpenAIRE |
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