Reconstruction of the three-dimensional beat pattern underlying swimming behaviors of sperm
| Autor: | Gerhard Gompper, Luis Alvarez, Ulrich Benjamin Kaupp, Benjamin M. Friedrich, Jens Elgeti, An Gong, Sebastian Rode |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Axoneme Male Eukaryotic flagellum Biophysics Beat (acoustics) 02 engineering and technology Flagellum Curvature Quantitative Biology::Cell Behavior Quantitative Biology::Subcellular Processes 03 medical and health sciences Humans General Materials Science ddc:530 Swimming Physics Physics::Biological Physics Holographic imaging Surfaces and Interfaces General Chemistry 021001 nanoscience & nanotechnology Sperm Spermatozoa 030104 developmental biology Classical mechanics Flagella 0210 nano-technology Regular Article - Living Systems Biotechnology |
| Zdroj: | The European Physical Journal. E, Soft Matter The European physical journal / E 44(7), 87 (2021). doi:10.1140/epje/s10189-021-00076-z |
| ISSN: | 1292-895X 1292-8941 |
| Popis: | Abstract The eukaryotic flagellum propels sperm cells and simultaneously detects physical and chemical cues that modulate the waveform of the flagellar beat. Most previous studies have characterized the flagellar beat and swimming trajectories in two space dimensions (2D) at a water/glass interface. Here, using refined holographic imaging methods, we report high-quality recordings of three-dimensional (3D) flagellar bending waves. As predicted by theory, we observed that an asymmetric and planar flagellar beat results in a circular swimming path, whereas a symmetric and non-planar flagellar beat results in a twisted-ribbon swimming path. During swimming in 3D, human sperm flagella exhibit torsion waves characterized by maxima at the low curvature regions of the flagellar wave. We suggest that these torsion waves are common in nature and that they are an intrinsic property of beating axonemes. We discuss how 3D beat patterns result in twisted-ribbon swimming paths. This study provides new insight into the axoneme dynamics, the 3D flagellar beat, and the resulting swimming behavior. Graphic abstract |
| Databáze: | OpenAIRE |
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