Elucidation of obstructive sleep apnoea related blood pressure surge using a novel continuous beat-to-beat blood pressure monitoring system
| Autor: | Richard B. Berry, Daichi Shimbo, Patrick Stafford, Heather Bonner, Ali Azarbarzin, Robert M. Carey, Martin Baruch, Sung-Ha Park, Sula Mazimba, Gen-Min Lin, Younghoon Kwon, Yeilim Cho, David A. Calhoun, Jeongok G. Logan |
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| Rok vydání: | 2023 |
| Předmět: |
Male
medicine.medical_specialty Physiology medicine.medical_treatment Polysomnography Blood Pressure Article Internal medicine Internal Medicine medicine Humans Sleep study Continuous positive airway pressure Respiratory system Sleep Apnea Obstructive medicine.diagnostic_test Continuous Positive Airway Pressure business.industry Blood Pressure Determination Middle Aged medicine.disease Blood pressure Cardiology Sleep (system call) Cardiology and Cardiovascular Medicine business Beat (music) Hypopnea |
| Zdroj: | J Hypertens |
| ISSN: | 1473-5598 |
| Popis: | BACKGROUND Obstructive sleep apnoea (OSA) episode related blood pressure (BP) surge may mediate the association of OSA with cardiovascular disease. However, BP is not measured during a clinical sleep study. METHOD We tested the feasibility of incorporating the Caretaker physiological monitor, which utilizes a novel continuous beat-to-beat (b-b) BP monitoring technology, into polysomnography (PSG) and aimed to characterize BP surges related to obstructive respiratory events. B-b BP was concurrently collected and merged with PSG data on a posthoc basis. We compared BP surge between mean respiratory (apnoea, hypopnea and desaturation-alone events) and nonrespiratory events (spontaneous or leg movement-related arousals). We examined the association of the degree of oxygen desaturation with BP surge in a given respiratory event combining all events. A total of 17 consecutive patients (12 men, mean 52 years old, nine diagnostic and eight split-night PSGs) undergoing clinically indicated PSG were included after excluding one patient with poor signal quality due to excessive movement. RESULTS Caretaker was well tolerated. Mean respiratory BP surge ranged from 5 to 19 mmHg [Median (IQR) = 13.9 (9.5--16.2)]. Mean BP surge between the respiratory and nonrespiratory events was similar [13.8 (4.5) vs. 14.9 (5.3) mmHg, P = 0.13]. Accounting for the count distribution of desaturation/BP surge data pair events, there was a linear correlation between the degree of oxygen desaturation and BP surge (R = 0.57, P |
| Databáze: | OpenAIRE |
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