Classification and coding of platelet-rich plasma derived from New Zealand white rabbits for tissue engineering and regenerative medicine applications
| Autor: | Med Ram Verma, Khan Sharun, A.M. Pawde, E. Kalaiselvan, Amarpal, Prakash Kinjavdekar, Amitha Banu S, Rohit Kumar, K. M. Manjusha |
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| Rok vydání: | 2021 |
| Předmět: |
Pharmacology
Blood Platelets Pathology medicine.medical_specialty Tissue Engineering business.industry Platelet Count Platelet-Rich Plasma Clinical Biochemistry Regenerative Medicine Regenerative medicine Tissue engineering Platelet-rich plasma Drug Discovery Medicine Animals Platelet concentrate New zealand white Rabbits business |
| Zdroj: | Expert opinion on biological therapy. 21(11) |
| ISSN: | 1744-7682 |
| Popis: | Platelet-rich plasma (PRP) is a category of platelet concentrate that has been widely used as a therapeutic modality in musculoskeletal medicine. The present study was conducted to classify and code the non-activated platelet-rich plasma (nPRP) derived from New Zealand white rabbits for tissue engineering and other regenerative medicine applications.PRP was prepared from the whole blood by double centrifugation protocol using a laboratory centrifuge. The prepared nPRP was characterized using the parameters such as platelet dose, the relative composition of platelets, WBC, and RBC. The production protocol was described using the parameters such as platelet enrichment factor, factor increase in WBC concentration, platelet capture efficiency, WBC-reducing efficiency, and RBC-reducing efficiency. The nPRP was also classified and coded using the most recent and universally accepted classification and coding systems.The non-activated leukocyte-poor red cell-rich PRP had an average platelet count of 1875.75 × 10The protocol described in this study can be used to prepare non-activated leukocyte-poor red cell-rich PRP (Red-PRP IC1) from rabbits that can be coded as 318-00-00. |
| Databáze: | OpenAIRE |
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