901-52 Ultrasonic Integrated Backscatter Cyclic Variations During Atrial Pacing in Patients with and without Coronary Artery Disease
| Autor: | Vito Marangelli, Paolo Rizzon, Sabino Iliceto, Cataldo Memmola, Leonarda Galiuto, VF Napoli |
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| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
Contraction (grammar) business.industry Ischemia medicine.disease Chest pain Coronary arteries Coronary artery disease medicine.anatomical_structure Coronary occlusion Internal medicine medicine Cardiology Ultrasonic sensor medicine.symptom Integrated backscatter business Cardiology and Cardiovascular Medicine |
| Zdroj: | Journal of the American College of Cardiology. 25(2) |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/0735-1097(95)91529-7 |
| Popis: | Contraction and relaxation of normal myocardium are associated with parallel integrated backscatter cyclic variations (IB CV). It has been demonstrated that IB CV are reversibly reduced in magnitude during coronary occlusion and reperfusion. To evaluate in humans the effects of pacing-induced ischemia on IB Cv, 29 pts were studied with multiplane TEE and simultaneous atrial pacing (up to 150 beats/m’). A prototype (Hewlett-Packard AD system) was used to acquire and analyse IB images. In each pt a transgastric 2 chamber view was acquired at rest, at peak-pacing and 5 cardiac cycles after pacing interruption (recovery). Twenty-one pts had significant coronary stenosis (≥50% narrowing): 8 pts developed myocardial ischemia (chest pain, ECG changes and wall motion abnormalities) during atrial-pacing [Group A], while the remaining 13 pts did not [Group B]. Eight pts had normal coronaries and no myocardial ischemia during pacing [Group C]. IB CV analysis was performed only in myocardial segments perpendicular to ultrasonic beam (anterior and inferior wall in transgastric view). In group A and B pts only segments within a territory supplied by a stenotic coronary artery were considered. Results IB CV are expressed in decibel units Download high-res image (64KB) Download full-size image Conclusion atrial pacing does not affect IB CV in myocardium supplied by normal coronary arteries. During pacing, IB CV are blunted in myocardium supplied by significantly narrowed coronary arteries, even in the absence of traditional signs of ischemia. IB CV have a potential in the identification of stress-induced regional left ventricular dysfunction in pts with coronary artery disease. |
| Databáze: | OpenAIRE |
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