Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case Report
| Autor: | Julia Fantana, Jan Beyer-Westendorf, Martin Koch, Simone von Bonin, Jan Moritz Middeke, Sybille Fuld |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Economics and Econometrics
2019-20 coronavirus outbreak Pediatrics medicine.medical_specialty Coronavirus disease 2019 (COVID-19) itp associated with covid vaccination secondary itp Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Case Report thrombocytopenia 030204 cardiovascular system & hematology infectious diseases itp associated with astrazeneca covid vaccination 03 medical and health sciences 0302 clinical medicine Immune system Materials Chemistry Media Technology medicine Diseases of the circulatory (Cardiovascular) system itp aquired business.industry Forestry platelet pathology / inherited Immune thrombocytopenia Public attention Vaccination RC666-701 030220 oncology & carcinogenesis Hemorrhagic complication covid vaccination business |
| Zdroj: | TH Open, Vol 05, Iss 03, Pp e315-e318 (2021) TH Open: Companion Journal to Thrombosis and Haemostasis |
| ISSN: | 2512-9465 |
| DOI: | 10.1055/s-0041-1731774 |
| Popis: | Novel mRNA and vector-based covid-19 vaccinations have shown high efficacy in preventing symptomatic COVID-19 infections. Compared with the number of performed vaccinations, rates of severe side effects seem low. Rare prothrombotic coagulation disorders with suspected association to ChAdOx1 nCoV-19 (AstraZeneca) have been reported. These cases have gathered considerable media attention and caused a temporary pause of usage of the AstraZeneca vaccine in Europe and several other countries and are currently discussed as vaccine-induced immune thrombotic thrombocytopenia (VITT). However, hemorrhagic complications from ChAdOx1 nCoV-19 vaccination have also been reported but, so far, received less public attention despite considerable potential for life-threatening complications. Here we present a case of severe immune thrombocytopenia after ChAdOx1 covid-19 vaccination and its successful primary management. |
| Databáze: | OpenAIRE |
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