Cell-mediated immunity in Darier's disease
Autor: | R. Steven Padilla, Arthur D. Bankhurst, Larry E. Becker, John C. Henry |
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Rok vydání: | 1979 |
Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent T-Lymphocytes T cell Dermatology Disease Skin infection Lymphocyte Activation Delayed hypersensitivity skin tests Leukocyte Count Immunity medicine Darier's disease Humans Skin Tests Immunity Cellular integumentary system business.industry Middle Aged medicine.disease Cell mediated immunity medicine.anatomical_structure Immunology Female business Darier Disease |
Zdroj: | Journal of the American Academy of Dermatology. 1:348-351 |
ISSN: | 0190-9622 |
DOI: | 10.1016/s0190-9622(79)70028-4 |
Popis: | Darier's disease, often complicated by skin infections, has been linked with a depressed cell-mediated immunity. Four moderate to severely affected patients with a negative history of skin infections were studied. T cell function was evaluated by Standard delayed hypersensitivity skin tests, enumeration of peripheral T cells, and mitogen-stimulated proliferation assays. No defect in cell-mediated immunity was found. The significance of the results when compared with prior studies is discussed. |
Databáze: | OpenAIRE |
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