| Autor: |
El-Hadi Zerdazi, Emmanuel Curis, Emily Karsinti, Romain Icick, Maeva Fortias, Philippe Batel, Olivier Cottencin, Cyrille Orizet, Aurélia Gay, Philippe Coeuru, Alice Deschenau, Philippe Lack, Delphine Moisan, Anne-Laure Pelissier-Alicot, Arnaud Plat, Jean-Baptiste Trabut, Isabelle Kousignian, Luana Boumendil, Eric Vicaut, Nathalie Prince, Jean-Louis Laplanche, Frank Bellivier, Jean-Pierre Lépine, Cynthia Marie-Claire, Georges Brousse, Florence Vorspan, Vanessa Bloch |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Drug and alcohol dependence. 232 |
| ISSN: |
1879-0046 |
| Popis: |
Cocaine-induced transient hallucinations (CIH) are a frequent complication following cocaine intake that is associated with addiction severity.Two hundred and forty-two non-psychotic and Caucasian lifetime cocaine users were included in a French multicentric study. Clinical variables and dopamine pathway genotype data were extracted and tested with CIH scores using a zero-inflated binomial model, which allows for the exploration of factors associated with occurrence and severity separately.Cocaine dependence (pOur study shows that CIH occurrence and severity are two distinct phenotypes, with shared clinical risk factors; however, they likely do not share the same genetic background. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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