Influence of Fasting on Intestinal Permeability and Disease Activity in Patients with Rheumatoid Arthritis
| Autor: | Folke D. Lindström, Lars Sköldstam, Inger Stjernström, Karl-Eric Magnusson, Christer Tagesson, Tommy Sundqvist |
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| Rok vydání: | 1982 |
| Předmět: |
medicine.medical_specialty
Time Factors Intestinal permeability business.industry Immunology Lactovegetarian diet Arthritis Fasting General Medicine medicine.disease Permeability Polyethylene Glycols Arthritis Rheumatoid Intestines Disease activity Endocrinology Intestinal Absorption Rheumatology Rheumatoid arthritis Internal medicine Humans Immunology and Allergy Medicine In patient business |
| Zdroj: | Scandinavian Journal of Rheumatology. 11:33-38 |
| ISSN: | 1502-7732 0300-9742 |
| DOI: | 10.3109/03009748209098111 |
| Popis: | We have investigated the influence of fasting and lactovegetarian diet on intestinal and non-intestinal permeability in 5 patients with rheumatoid arthritis. We used low-molecular weight polyethyleneglycols (PEG 400) as probe molecules and a deterministic mathematical model to assess the permeability characteristics. Both intestinal and non-intestinal permeability decreased after fasting, but increased again during a subsequent lactovegetarian diet regime. Concomitantly it appeared that disease activity, as shown by a clinical six-joint score, first decreased and then increased again. The results indicate that, unlike lactovegetarian diet, fasting may ameliorate the disease activity and reduce both the intestinal and the non-intestinal permeability in rheumatoid arthritis. |
| Databáze: | OpenAIRE |
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