Effect of type of diet on blood and plasma taurine concentrations, cardiac biomarkers, and echocardiograms in 4 dog breeds
| Autor: | Michael Aherne, Michelle Vereb, Rebecca L. Stepien, Robert J. Goldberg, John E. Rush, Lisa M. Freeman, Darcy B. Adin, S.S. Tjostheim, Heidi B. Kellihan |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Taurine
040301 veterinary sciences medicine.drug_class Cardiac biomarkers Cardiology Physiology Standard Article 030204 cardiovascular system & hematology NT‐proBNP 0403 veterinary science 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Dogs grain free Interquartile range Natriuretic Peptide Brain Natriuretic peptide Medicine Animals Dog Diseases Whole blood grain inclusive lcsh:Veterinary medicine General Veterinary biology business.industry troponin food Dilated cardiomyopathy 04 agricultural and veterinary sciences medicine.disease Troponin Breed Peptide Fragments Standard Articles Diet dilated cardiomyopathy Plant Breeding Cross-Sectional Studies chemistry Echocardiography biology.protein lcsh:SF600-1100 SMALL ANIMAL business Biomarkers |
| Zdroj: | Journal of Veterinary Internal Medicine, Vol 35, Iss 2, Pp 771-779 (2021) Journal of Veterinary Internal Medicine |
| ISSN: | 0891-6640 1939-1676 |
| Popis: | Background Associations of diet with dilated cardiomyopathy are under investigation. Objectives That cardiac assessment would show abnormalities in healthy dogs eating grain‐free (GF) diets or diets with Food and Drug Administration (FDA)‐listed ingredients of concern (peas, lentils, or potatoes) as top 10 ingredients (FDA‐PLP), but not in dogs eating grain‐inclusive (GI) diets or diets without FDA‐listed ingredients of concern (PLP) in the top 10 ingredients (NoFDA‐PLP). Animals One hundred eighty‐eight healthy Doberman Pinschers, Golden Retrievers, Miniature Schnauzers, and Whippets. Methods This study was an observational cross‐sectional study. Echocardiograms, cardiac biomarkers, and blood and plasma taurine concentrations were compared between dogs eating GF (n = 26) and GI (n = 162) diets, and between FDA‐PLP (n = 39) and NoFDA‐PLP (n = 149) diets, controlling for age and breed. Demographic characteristics, murmurs, genetic status, and ventricular premature complexes (VPCs) during examination were compared between dogs eating different diet types. Results No differences in echocardiographic variables, N‐terminal pro‐B‐type natriuretic peptide or whole blood taurine were noted between dogs eating different diet types. Dogs eating GF diets had higher median high‐sensitivity cardiac troponin I (hs‐cTnI) (GF 0.076 ng/mL [Interquartile range (IQR), 0.028‐0.156] vs. GI 0.048 [IQR, 0.0026‐0.080]; P |
| Databáze: | OpenAIRE |
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