Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review
| Autor: | Nafsika Simou, Ifigenia Tasiou, Dimitrios Ntaskagiannis, Antonio Capizzello, Periklis Tsekeris, Evangelia Peponi, Sevasti Kamina |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Small cell carcinoma
Pathology medicine.medical_specialty Prostate cancer biology business.industry Thyroid medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Neuroendocrine differentiation Small-cell carcinoma lcsh:RC254-282 Published: February 2011 medicine.anatomical_structure Oncology Antigen Prostate medicine Synaptophysin biology.protein business Immunostaining |
| Zdroj: | Case Reports in Oncology, Vol 4, Iss 1, Pp 88-95 (2011) Case Reports in Oncology |
| ISSN: | 1662-6575 |
| Popis: | Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cells exhibited positivity for pancytokeratin, synaptophysin, thyroid transcription factor-1 and CD56. Immunostaining for prostate-specific antigen was negative, while serum prostate-specific antigen was within normal limits. We review the available literature to gain additional information about diagnosis, treatment and prognosis of pure SCPCa. |
| Databáze: | OpenAIRE |
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