Pathogenesis of Experimental Endocarditis
| Autor: | Larry M. Baddour, W A Simpson, Gordon D. Christensen, J H Lowrance |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Microbiology (medical)
Cardiac Catheterization medicine.medical_specialty Bacteria business.industry Colony Count Microbial Host response Endocarditis Bacterial medicine.disease Pathogenesis Disease Models Animal Catheters Indwelling Infectious Diseases Infective endocarditis Heart catheterization Indwelling catheter Immunology Colony count medicine Animals Endocarditis Intensive care medicine business Endocardium |
| Zdroj: | Clinical Infectious Diseases. 11:452-463 |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1093/clinids/11.3.452 |
| Popis: | Numerous important observations concerning the pathogenesis of infective endocarditis have been made over the past 18 years. Many of these observations have been obtained with animal models of endocarditis in which an indwelling catheter has been used to produce predisposing endocardial lesions for subsequent infection. Unlike several previously used animal models, the catheter-induced endocarditis models have many characteristics similar to infective endocarditis in humans. Key findings regarding microbial adherence and persistence and the host response to endocardial infection have led to a better appreciation of the complex issues operative in the pathogenesis of endocarditis. |
| Databáze: | OpenAIRE |
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