Outbreak of Clostridium difficile -related diarrhoea in an adult oncology unit: risk factors and microbiological characteristics

Autor: D Besson, F. Barbut, E. Blot, Bernard Asselain, Pierre Pouillart, C Granpeix, M.C. Falcou, M.-C Escande
Rok vydání: 2003
Předmět:
Zdroj: Journal of Hospital Infection. 53:187-192
ISSN: 0195-6701
DOI: 10.1053/jhin.2002.1356
Popis: We describe the risk factors and microbiological findings of an outbreak of Clostridium difficile (CD)-related diarrhoea in the Medical Oncology Department of the Curie Institute. Screening for CD in stools was performed on 59 patients with diarrhoea and 146 patients without diarrhoea. Toxin secretion, serotyping (enzyme-linked immunosorbant assay) and genotyping (AP-polymerase chain reaction) were performed on 39 CD strains from 32 patients. The risk factors for toxigenic CD-positive diarrhoea were also investigated. Twenty-seven (46%) patients with diarrhoea and 12 (8%) patients without diarrhoea were CD-positive (P
Databáze: OpenAIRE