Outbreak of Clostridium difficile -related diarrhoea in an adult oncology unit: risk factors and microbiological characteristics
Autor: | D Besson, F. Barbut, E. Blot, Bernard Asselain, Pierre Pouillart, C Granpeix, M.C. Falcou, M.-C Escande |
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Rok vydání: | 2003 |
Předmět: |
Adult
DNA Bacterial Diarrhea Male Microbiology (medical) Serotype Oncology Paris medicine.medical_specialty Time Factors Genotype medicine.drug_class Antibiotics Antineoplastic Agents Polymerase Chain Reaction Disease Outbreaks Age Distribution Risk Factors Neoplasms Oncology Service Hospital Internal medicine medicine Humans Serotyping Risk factor Genotyping Enterocolitis Pseudomembranous Antibacterial agent Cross Infection Infection Control Clostridioides difficile business.industry digestive oral and skin physiology Academies and Institutes Outbreak General Medicine Middle Aged Clostridium difficile Anti-Bacterial Agents Infectious Diseases Case-Control Studies Female medicine.symptom business |
Zdroj: | Journal of Hospital Infection. 53:187-192 |
ISSN: | 0195-6701 |
DOI: | 10.1053/jhin.2002.1356 |
Popis: | We describe the risk factors and microbiological findings of an outbreak of Clostridium difficile (CD)-related diarrhoea in the Medical Oncology Department of the Curie Institute. Screening for CD in stools was performed on 59 patients with diarrhoea and 146 patients without diarrhoea. Toxin secretion, serotyping (enzyme-linked immunosorbant assay) and genotyping (AP-polymerase chain reaction) were performed on 39 CD strains from 32 patients. The risk factors for toxigenic CD-positive diarrhoea were also investigated. Twenty-seven (46%) patients with diarrhoea and 12 (8%) patients without diarrhoea were CD-positive (P |
Databáze: | OpenAIRE |
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