Right ventricular strain in repaired Tetralogy of Fallot with regards to pulmonary valve replacement
| Autor: | Francesco Secchi, Mario Carminati, Davide Capra, Caterina Beatrice Monti, Francesco Sardanelli, Giulia Lastella, Ugo Barbaro, Gianluca Guarnieri |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Strain (injury) 030218 nuclear medicine & medical imaging Free wall Young Adult 03 medical and health sciences 0302 clinical medicine Interquartile range Internal medicine Pulmonary Valve Replacement medicine Humans Radiology Nuclear Medicine and imaging In patient Longitudinal Studies Retrospective Studies Tetralogy of Fallot Heart Valve Prosthesis Implantation Pulmonary Valve medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine medicine.disease Treatment Outcome medicine.anatomical_structure 030220 oncology & carcinogenesis Pulmonary valve Ventricular Function Right Cardiology Female business |
| Zdroj: | European Journal of Radiology. 131:109235 |
| ISSN: | 0720-048X |
| Popis: | Purpose To assess right ventricular (RV) myocardial strain both globally and segmentally through feature-tracking cardiac magnetic resonance (CMR) in patients with Tetralogy of Fallot (ToF), with regards to pulmonary valve replacement (PVR). Methods After Ethics Committee approval, we retrospectively included 46 consecutive ToF patients who had two CMR examinations performed at our institution between March 2014 and June 2019. We divided patients into those who had not undergone PVR between the two CMR examinations (Group-0), and those who had (Group-1). Ventricular volumes were quantified on cine sequences, and strain was calculated through feature-tracking, using the previously traced segmentations. RV longitudinal and radial strain were assessed both globally and separately for the septum and free wall. Variations were normalized for intercurrent years, differences were appraised with t-tests or Mann-Whitney U. Results 30 patients belonged to Group-0 and 16 to Group-1. Median age was 22 years (interquartile range [IQR] 17–29 years) in Group-0, and 21 years (IQR 16–29 years) in Group-1. No significant differences were reported in RV strain between groups (p ≥ 0.254) except for RV septal radial strain, significantly higher (p = 0.010) in Group-0 (24.2 %, IQR 10.1–52.4 %) than in Group-1 (6.0 %, IQR −3.3–23.3 %) at the second CMR. Both global and segmental RV strains decreased over time in both groups, and yearly variations did not differ significantly (p ≥ 0.081) between groups. Conclusions While PVR performed at the appropriate timing eases the burden on the RV allowing for a reduction in volumes, RV strain seems to continuously deteriorate as in patients who do not undergo PVR. |
| Databáze: | OpenAIRE |
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