Extracolonic findings in an asymptomatic screening population undergoing intravenous contrast-enhanced computed tomography colonography
| Autor: | Donghee Kim, Kyoung Soo Cho, Kyung Ran Cho, In Sung Song, Seon Hee Lim, Sang Heon Cho, Chung Hyeon Kim, Hyun Chae Jung, Sun Sin Kim, Young Sun Kim, Byung Hee Oh, Nayoung Kim, Seung Ho Choi, Soo Young Kim, Min Jung Park, Chan Soo Shin, Jeong Hoon Kim, Byung I. Choi, Jeong Yoon Yim |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Colon Cost-Benefit Analysis Population Contrast Media Urogenital System Kidney Asymptomatic Medical Records Esophagus Predictive Value of Tests Computed Tomography Colonography Neoplasms Adrenal Glands Humans Mass Screening Medicine Prospective Studies Biliary Tract education Prospective cohort study Lung Pancreas Aged Aged 80 and over education.field_of_study Hepatology business.industry Medical record Stomach Gastroenterology Middle Aged medicine.disease Contrast medium Early Diagnosis Liver Predictive value of tests Injections Intravenous Blood Vessels Female Radiology Mucinous Tumor medicine.symptom Colorectal Neoplasms Tomography X-Ray Computed business |
| Zdroj: | Journal of Gastroenterology and Hepatology. 23:e49-e57 |
| ISSN: | 1440-1746 0815-9319 |
| DOI: | 10.1111/j.1440-1746.2007.05060.x |
| Popis: | Background and Aim: The purpose of this study was to evaluate extracolonic findings that could be encountered with computed tomography colonography (CTC) using intravenous (IV) contrast material in an asymptomatic screening population. Methods: Intravenous contrast medium-enhanced CTC was performed in 2230 asymptomatic adults (mean age, 57.5 years). Axial images were prospectively examined for extracolonic lesions. These findings were classified into three categories: potentially important findings, likely unimportant findings, and clinically unimportant findings. Potentially important extracolonic findings were defined as those which required immediate further diagnostic studies and treatment. Clinical and radiologic follow up, missed lesions and clinical outcomes were assessed using medical records (mean duration of follow up, 1.6 years). Results: A total of 115 new potentially important findings in 5.2% of subjects (115/2230) were found. Subsequent medical or surgical intervention was performed in 2.0% (45/2230). New extracolonic cancer was detected in 0.5% (12/2230), and the majority of them (83.3%) were not metastasized. Computed tomography colonography missed eight potentially important extracolonic findings in eight subjects (0.4%, 8/2230): 0.8-cm early-stage prostatic cancer, six adrenal mass and one intraductal papillary mucinous tumor. There were no severe life-threatening complications related to contrast medium. Conclusion: Intravenous contrast-enhanced CTC could safely detect asymptomatic early-stage extracolonic malignant diseases without an unreasonable number of additional work-ups, thus reducing their morbidity or mortality. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text