Translocation t(3;12)(q28;q14) in parosteal lipoma
| Autor: | Julia A. Bridge, Joanne DeBoer, James R. Neff, Craig W. Walker |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Cancer Research
Chromosomes Human Pair 12 Femoral Neoplasms Chromosome Mapping Soft tissue Chromosomal translocation Anatomy Middle Aged Lipoma Biology medicine.disease Translocation Genetic body regions stomatognathic diseases Parosteal lipoma Karyotyping otorhinolaryngologic diseases Genetics medicine Humans Female Femur Chromosomes Human Pair 3 |
| Zdroj: | Genes, Chromosomes and Cancer. 12:70-72 |
| ISSN: | 1098-2264 1045-2257 |
| Popis: | Parosteal lipoma is a rare primary benign bone tumor demonstrating histopathologic features similar to those seen in the commonly occurring lipoma of soft tissue. Cytogenetic studies of soft tissue lipoma have demonstrated frequent abnormalities of 12q13-15. To the best of our knowledge the cytogenetic findings in parosteal lipoma have not yet been described. Cytogenetic analysis of a parosteal lipoma of the femur of a 51-year-old female revealed a t(3;12)(q28;q14), indicating that bone and soft tissue lipomas are cytogenetically similar and likely share a common histopathogenesis. |
| Databáze: | OpenAIRE |
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