Rupture of the Pleomorphic Adenoma of the Parotid Gland: What to Know before, during and after Surgery

Autor:	Vito D'Andrea, Antonio Greco, Marc Remacle, Michele Grasso, Marco de Vincentiis, Domenico Di Maria, Paolo Petrone, Massimo Ralli, Giulia De Soccio, Antonio Minni, Fabrizio Cialente, Massimo Fusconi, Griselda Agolli
Rok vydání:	2021
Předmět:	pleomorphic adenoma medicine.medical_specialty business.industry Tumor Spillage General Medicine Parotidectomy medicine.disease parotid capsule Article Surgery Parotid gland Resection superficial parotidectomy recurrence of pleomorphic adenoma intraoperative spillage Pleomorphic adenoma Tumor rupture Spillage medicine.anatomical_structure Superficial Parotidectomy medicine Medicine business
Zdroj:	Journal of Clinical Medicine Journal of Clinical Medicine, Vol 10, Iss 5368, p 5368 (2021) Volume 10 Issue 22
ISSN:	2077-0383
Popis:	Background: We assessed the cases of intraoperative spillage of primary pleomorphic adenomas (PPAs) of the parotid gland in the literature, comparing them with our own cases. We aim to explain how the surgeon should manage a spillage during surgery (i.e., how to avoid spreading the contents that are coming out of the tumor). We also aim to investigate whether or not spillage is linked to a higher rate of PPA recurrence. Methods: We collected surgical and pathological reports, taking data on capsular ruptures and the spillage of tumors. Results: Intraoperative tumor spillage and tumor rupture occurred in 34/202 cases. There were three recurrences after a mean of 3.7 years (mean follow-up duration: 10.3 years). One recurrence happened to a patient who had an intraoperative tumor spillage, and two more recurrences happened to patients who did not have spillage. Conclusion: We believe that the real number of the events of spillage is underestimated and underreported by surgeons. Capsular rupture must always be avoided, and secure resection margins must always be pursued, independent of the type of parotidectomy being performed. Features that increase the risk of recurrence are an intraoperative rupture and the presence of satellite nodules (as recorded in the pathologist’s report). In these cases, patients need a longer follow-up period.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2943febf823c3124d1426d827ed94a7f https://pubmed.ncbi.nlm.nih.gov/34830650 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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