Efficacy of a randomized trial examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women

Autor: Richard B. Kreider, Elfego Galvan, Chris Rasmussen, Ryan Dalton, Mike Greenwood, Majid Koozehchian, Sunday Simbo, Adriana M. Coletta, Brittanie Lockard, Andrew R. Jagim, Kyle Levers, Deepesh Khanna, Julie Y. Kresta, C Baetge, Michael J. Byrd, Jonathan M. Oliver, Brittany Sanchez, Conrad P. Earnest, Y. Peter Jung
Rok vydání: 2017
Předmět:
medicine.medical_specialty
Diet
Reducing
Physiology
Endocrinology
Diabetes and Metabolism
030209 endocrinology & metabolism
Overweight
Body Mass Index
law.invention
03 medical and health sciences
0302 clinical medicine
Double-Blind Method
Randomized controlled trial
Risk Factors
law
Weight loss
Physiology (medical)
Internal medicine
Weight Loss
Prevalence
medicine
Chi-square test
Humans
Obesity
030212 general & internal medicine
Exercise
Metabolic Syndrome
Nutrition and Dietetics
business.industry
Resistance Training
General Medicine
Middle Aged
medicine.disease
Combined Modality Therapy
Texas
Confidence interval
Cardiorespiratory Fitness
Physical therapy
Patient Compliance
Female
Insulin Resistance
Sedentary Behavior
medicine.symptom
Metabolic syndrome
Energy Intake
business
Body mass index
Follow-Up Studies
Zdroj: Applied Physiology, Nutrition, and Metabolism. 42:216-227
ISSN: 1715-5320
1715-5312
DOI: 10.1139/apnm-2016-0456
Popis: While commercial dietary weight-loss programs typically advise exercise, few provide actual programing. The goal of this study was to compare the Curves Complete 90-day Challenge (CC, n = 29), which incorporates exercising and diet, to programs advocating exercise (Weight Watchers Points Plus (WW, n = 29), Jenny Craig At Home (JC, n = 27), and Nutrisystem Advance Select (NS, n = 28)) or control (n = 20) on metabolic syndrome (MetS) and weight loss. We randomized 133 sedentary, overweight women (age, 47 ± 11 years; body mass, 86 ± 14 kg; body mass index, 35 ± 6 kg/m2) into respective treatment groups for 12 weeks. Data were analyzed using chi square and general linear models adjusted for age and respective baseline measures. Data are means ± SD or mean change ± 95% confidence intervals (CIs). We observed a significant trend for a reduction in energy intake for all treatment groups and significant weight loss for all groups except control: CC (−4.32 kg; 95% CI, −5.75, −2.88), WW (−4.31 kg; 95% CI, −5.82, −2.96), JC (−5.34 kg; 95% CI, −6.86, −3.90), NS (−5.03 kg; 95% CI, −6.49, −3.56), and control (0.16 kg, 95% CI, −1.56, 1.89). Reduced MetS prevalence was observed at follow-up for CC (35% vs. 14%, adjusted standardized residuals (adjres.) = 3.1), but not WW (31% vs. 28% adjres. = 0.5), JC (37% vs. 42%, adjres. = −0.7), NS (39% vs. 50% adjres. = −1.5), or control (45% vs. 55% adjres. = −1.7). While all groups improved relative fitness (mL·kg−1·min−1) because of weight loss, only the CC group improved absolute fitness (L/min). In conclusion, commercial programs offering concurrent diet and exercise programming appear to offer greater improvements in MetS prevalence and cardiovascular function after 12 weeks of intervention.
Databáze: OpenAIRE
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