Comparative Effects of Diltiazem and Lisinopril on Left Ventricular Structure and Filling in Mild-to-Moderate Hypertension
| Autor: | Ki Lie, AJ Smit, Hpm Hamer, TK Havinga, F. H. Schuurman, Bs Tenberge, Jf May, Harry Wesseling, E Vanderveur, Jtm Vanleeuwen |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Male medicine.medical_specialty Ambulatory blood pressure Diastole Angiotensin-Converting Enzyme Inhibitors Physical exercise Doppler echocardiography Ventricular Function Left Diltiazem Double-Blind Method Lisinopril Internal medicine medicine Humans Aged Pharmacology medicine.diagnostic_test business.industry Middle Aged Calcium Channel Blockers Confidence interval Blood pressure Hypertension Cardiology Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine business circulatory and respiratory physiology medicine.drug |
| Zdroj: | Journal of Cardiovascular Pharmacology. 26:983-989 |
| ISSN: | 0160-2446 |
| DOI: | 10.1097/00005344-199512000-00020 |
| Popis: | The comparative effects on echocardiographically determined left ventricular (LV) mass and pulsed Doppler derived indexes of LV diastolic filling were studied in previously untreated hypertensive patients after 6 months of treatment with diltiazem 300 mg once daily (o.d.) (n = 16), and lisinopril 20 mg o.d. (n = 20). LV mass index decreased in the lisinopril group (from 92 to 82 g/m(2)), but not in the diltiazem group (from 98 to 96 g/m(2)); mean difference after 6 months of treatment with diltazem-lisinopril was 13.7 g/m(2) [95% confidence interval (CI) 0.8 to 26.6, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|