Pd-Catalyzed Decarbonylative Cross-Couplings of Aroyl Chlorides
| Autor: | Naoko Ichiishi, Christian A. Malapit, Melanie S. Sanford |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Carboxylic acid
Carboxylic Acids Naphthalenes 010402 general chemistry Benzoates 01 natural sciences Biochemistry Article Catalysis chemistry.chemical_compound Coordination Complexes Benzene Derivatives Organic chemistry Amines Physical and Theoretical Chemistry chemistry.chemical_classification 010405 organic chemistry Extramural Aryl Biphenyl Compounds Organic Chemistry Esters Oxidation reduction Boronic Acids 0104 chemical sciences chemistry Oxidation-Reduction Palladium Ethers |
| Zdroj: | Organic Letters. 19:4142-4145 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | This report describes a method for Pd-catalyzed decarbonylative cross-coupling that enables the conversion of carboxylic acid derivatives to biaryls, aryl amines, aryl ethers, aryl sulfides, aryl boronate esters, and trifluoromethylated arenes. The success of this transformation leverages the Pd0/Brettphos-catalyzed decarbonylative chlorination of aroyl chlorides, which can then participate in diverse cross-coupling reactions in situ using the same Pd catalyst. |
| Databáze: | OpenAIRE |
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