Isolation of SV40 from the environment of a colony of cynomolgus monkeys naturally infected with the virus
| Autor: | Rosina Girones, Philip D. Minor, Sílvia Bofill-Mas, Nestor Albinana-Gimenez, P.A. Pipkin |
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| Rok vydání: | 2004 |
| Předmět: |
viruses
Molecular Sequence Data Simian virus 40 Environment Biology Kidney Regulatory region Virus SV40 Feces Antigen Virology Animals Antigens Viral Tumor SV40 transmission Polyomavirus Infections Base Sequence Strain (chemistry) Transmission (medicine) Inoculation Primate Diseases Virion SV40 stability Cynomolgus Isolation (microbiology) SV40 infection Macaca fascicularis Tumor Virus Infections Mixed infection |
| Zdroj: | Virology. 330(1):1-7 |
| ISSN: | 0042-6822 |
| DOI: | 10.1016/j.virol.2004.09.007 |
| Popis: | The presence of SV40 viral particles in the environment of cynomolgus monkeys naturally infected with this virus has been analyzed by testing waste of the cage samples.SV40 was detected in 2/4 cages tested where mixed infection of SV40 and adenoviruses was observed after inoculation of virions concentrated from cage waste in CV-1 cells. The detected SV40 strains were identical in the regions studied to strain W17, isolated at National Institute for Biological Standards and Control, UK (NIBSC) from a (1/19) monkey kidney biopsy and contains an archetypal regulatory region. The recovery of infectious SV40 virions from the cages provides information about the potential mechanism of transmission of this virus. |
| Databáze: | OpenAIRE |
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