Haemodynamic Effects of Ethanol Immediately after Open-Heart Surgery of the Mitral Valve:A Clinical Study Peroperatively and in the Early Postoperative Period

Autor: S.-O. Nyström, L. Johansson, G. Klingen
Rok vydání: 1978
Předmět:
Zdroj: Scandinavian Journal of Thoracic and Cardiovascular Surgery. 12:169-176
ISSN: 0036-5580
DOI: 10.3109/14017437809100369
Popis: The haemodynamic effects of intravenous (i.v.) ethanol were studied in 8 patients (group II) in the early stages after open-heart surgery of the mitral valve. A group of 7 patients not treated with ethanol (group I) served as controls (Klingen et al., 1978 a). Continuous i.v. infusion of ethanol was started after termination of bypass and was given for 6 hours postoperatively with a blood concentration of about 20 mmol/1. The following reactions in group II during the postoperative period differed from the course in group I and may therefore have constituted the effects of ethanol administration. The arterial systemic blood pressure and the heart rate were lower (P < 0.05). The total peripheral vascular resistance was lower, lying at a normal level (P < 0.001). The pulmonary vascular resistance was lower (P < 0.05), cardiac index higher (P < 0.05) and stroke index also higher (P < 0.01). The left and right ventricular stroke work indices were higher, due solely to the significantly higher flow, as the sys...
Databáze: OpenAIRE