Intravenous Acetaminophen for Postoperative Pain Management in Patients Undergoing Living Laparoscopic Living-Donor Nephrectomy
| Autor: | Patricia Sheiner, William L. Baker, Spencer T. Martin, Elizabeth M. Tencza, Caroline Rochon, Van Vu |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment 030232 urology & nephrology Nephrectomy Patient Readmission 03 medical and health sciences 0302 clinical medicine 030202 anesthesiology Interquartile range medicine Living Donors Humans Pain Management Pharmacology (medical) Infusions Intravenous Kidney transplantation Acetaminophen Aged Pain Measurement Retrospective Studies Pain Postoperative business.industry digestive oral and skin physiology Retrospective cohort study Analgesics Non-Narcotic Length of Stay Middle Aged medicine.disease Kidney Transplantation Surgery Liver Transplantation Transplantation Analgesics Opioid Opioid Anesthesia Administration Intravenous Female Laparoscopy Complication business medicine.drug |
| Zdroj: | The Annals of pharmacotherapy. 51(1) |
| ISSN: | 1542-6270 |
| Popis: | Background: Postoperative pain is a common complication of laparoscopic living-donor nephrectomies (LLDNs). Objective: To determine whether intravenous (IV) acetaminophen administration post-LLDN influenced length of stay (LOS) when used for pain management. Methods: This single-center, retrospective study compared patients undergoing LLDN who had received IV acetaminophen for pain control versus those who did not between June 1, 2011, and November 30, 2015. Patient LOS, 30-day readmissions, frequency of pain assessments, patient-reported pain scores, and opioid administration were assessed. Results: A total of 90 patients were included in the analysis (IV acetaminophen, n = 48; non-IV acetaminophen, n = 42). Patients who did not receive IV acetaminophen were more often older (48.8 ± 12.1 vs 39.3 ± 12.1 years; P = 0.012) and female (71.4% vs 47.9%; P < 0.001). The average LOS was similar between the 2 groups (median = 3.0; interquartile range = [3, 4] vs 3.5 [3, 4]; P = 0.737). The 30-day readmissions were higher in the IV acetaminophen group (16.7%) compared with the group not receiving IV acetaminophen (2.4%; P = 0.033). After the first postoperative day, the frequencies of pain assessments performed were similar among the 2 groups. There was no difference in average pain scores between the groups at any time after LLDN. Conclusions: Patients receiving IV acetaminophen were found to have no improvements in hospital LOS, average pain score, or opioid requirements compared with patients not receiving IV acetaminophen. Patients who received IV acetaminophen were also found to have a higher 30-day readmission rate. |
| Databáze: | OpenAIRE |
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