Bisphosphonate-related atypical femoral fractures: A novel strategy to improve patient outcomes
| Autor: | A Simons, Rajpreet Sahemey, P Makrides, S Bhattacharya, AP Nikolaides |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Osteoporosis 030209 endocrinology & metabolism Physical Therapy Sports Therapy and Rehabilitation law.invention Intramedullary rod 03 medical and health sciences 0302 clinical medicine Atypical femoral fracture lcsh:Orthopedic surgery law medicine Orthopedics and Sports Medicine Femur Adverse effect 030222 orthopedics business.industry Rehabilitation Bisphosphonate medicine.disease Surgery lcsh:RD701-811 Delayed union Bisphosphonate therapy business |
| Zdroj: | Journal of Orthopaedics, Trauma and Rehabilitation, Vol 27 (2020) |
| ISSN: | 2210-4925 2210-4917 |
| Popis: | Background: Atypical femoral fracture (AFF) is a serious adverse event associated with bisphosphonate therapy and prone to complications and delayed union. We propose a technique and management strategy to maximise bone healing and outcomes. Methods: We report on a cohort of patients with AFF using our novel technique of preparing the intramedullary canal and rigid fixation with cephalomedullary nailing. Patients were admitted under a multidisciplinary team with rehabilitation goals of early mobilisation and teriparatide initiation. Clinical and radiographic data were retrospectively reviewed. Results: Twenty-eight AFFs were treated with a mean follow-up of 58.5 weeks and a mean age of 75.2 years old. All cases achieved radiological union by a mean of 6 months and post-operative thigh pain experienced up to 8.7 weeks. No cases underwent revision or experienced intraoperative complication. Conclusion: Our surgical technique and multidisciplinary management are reproducible with excellent results in patients with this rare yet challenging injury. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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